Saudi Pharmacist Licensing Exam Questions

Saudi Prometric SPLE exam preparation MCQs
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1) USP Compounded Preparation Monographs (CPMs ) provide information about:

A) Preparation Formulas (ingredients and quantities)
B) Directions to correctly compound the preparation
C) Beyond-use dates based on stability studies
D) Packaging and storage information
E) All of the above



2) Neurotransmitters can be classified based on their function which is either excitatory or inhibitory. Which of the following is classified as an inhibitory neurotransmitter?

A) Aspartate

B) Serotonin

C) Glutamate

D) Gama aminobutyric acid

E) Dopamine



3) The pharmacological effects of four antihypertensive drug classes (A-D) on the renin-angiotensin system are shown in the following table;

ParametersDrug-ADrug-BDrug-CDrug-D
Renin-Conc.🠋🠉🠉🠉
Angiotensin-I-Conc.🠋🠉🠉🠉
Angiotensin-II-Conc.🠋🠋🠉🠉
Angiotensin-Receptor------🠋---

Which class is represented by the drug -A?

A Diuretics
B Direct Renin inhibitors
C Angiotensin II receptor blockers
D Angiotensin-converting enzyme inhibitor
E) Adrenergics



4) Pathogenic microbial life causes many of the known diseases of the human system. Which of the following micro-organisms is causative of typhoid fever?

A) Shigella

B) Flavivirus

C) Salmonella

D) Treponema pallidum

E) E. coli



5) The compound 'Otilonium bromide' is indicated for the treatment of;

a) certain types of tumors

b) irritable bowel and painful spastic states

c) nausea and vomiting during chemotherapy

d) painful asthmatic states

e) third-degree skin burns



6) Calcium homeostasis regulates calcium flow to and from the bones. Which of the following substances plays a role in calcium homeostasis?

A) 1,25-dihydroxy cholecalciferol and calcitonin

B) 1,25-dihydroxy cholecalciferol and insulin

C) parathyroid hormone and glucagon

D) thyroid hormone and glucagon

E) Insulin and lipase



7) Which of the following pharmaco-economic studies is the simplest because the outcomes are assumed to be equivalent and only the costs of intervention are compared?

A) cost-utility analysis

B) cost-benefit analysis

C) cost-minimization analysis

D) cost-effectiveness analysis

E) cost-outcome analysis


8) Which of the following types of studies in medicine is more susceptible to recall bias?

A) Retrospective cohort study

B) Prospective cohort study

C) Randomized controlled trial

D) Non-randomized controlled trial\

E) Meta-analysis




9) USP Chapter <797> provides standards for:

A) compounding nonsterile preps
B) compounding sterile preps
C) handling of hazardous drugs in healthcare
D) storage conditions of pharmaceuticals during their lifetime
E) compounding and repackaging of radiopharmaceuticals




10) Which of the following scenarios is considered a violation of ethics?

A) Submitting a research approval extension request to the institutional review board after failing to finish the project within the approved period

B) Direct-to-consumer pharmaceutical advertising (DTCPA)

C) Calling patients to collect information after telling them about the project and getting their agreements

D) Drawing blood samples after getting approval from the institutional review board

E) Distributing questionnaires to patients waiting in emergency to collect information about their health status without a consent form




11) Which of the following communication techniques is the most appropriate at the message you want to deliver to a patient (or healthcare provider) is received correctly?

A) Feedback
B) Direct contact
C) High voice tone
D) Non-verbal communication
E) Body language



12) Narcotic drugs may cause dependence and addiction after repeated administration. Which of the following drugs is placed under the narcotic classification?

A) Pentobarbital
B) Midazolam
C) Loprazolam
D) Phenytoin 
E) Fentanyl



13) Which one of the following strategies is used with low literacy or illiterate patients to encourage them to change their behavior?

A) Keep information focused and organized
B) Use a normal speaking tone and volume
C) Use briefer educational sessions
D) Use more visual aids
E) Use the carrot and stick approach



14) A study design of randomized controlled trial or RCT has many advantages. Which of the following is the disadvantage of conducting a randomized controlled trial?

A) Expensive
B) High possibility of bias
C) Difficult to control confounders
D) Investigators can use multiple methods of randomization
E) Cannot be used for hypothesis testing



15) Which of the following is the most appropriate source for prescribed information on compounding medications?

A) Micromedex
B) Orange book
C) A drug information website
D) United states pharmacopeias (USP)
E) Pharmacist



16) For optimum results of a drug therapy, adherence on part of the patient is absolutely essential. Which of the following measurements is used to assess patient compliance?

A) Drug utilization reviews
B) Medication event system
C) Medication possession ratio
D) Medication therapy management
E) Review of drug side effects



17) USP chapters are given against their description in the options below Identify the INCORRECT match;

A) USP Chapter <795> standards for nonsterile preparations
B) USP Chapter <797> standards for sterile preparations
C) USP Chapter <800> standards for hazardous drugs handling
D) USP Chapter <825> standards for radiopharmaceuticals
E) USP Chapter <839> standards for packaging materials



18) Which of the following immunoglobulin (Ig) is frequently found to be elevated in asthmatic patients?

A) IgA
B) IgE
C) IgM
D) IgD
E) IgG



19) Which governing body is responsible to promote public health in Saudi Arabia?

A) Saudi Food and Drug Authority
B) Ministry of Education
C) Ministry of Health
D) Health Colleges
E) Saudi Health Authority



20) The type of study that considers data from multiple studies of different designs to draw conclusions is;

A) Case Series
B) Double-blind study
C) Systematic review
D) Consensus statement
E) Non-randomized Controlled Study



21) USP has developed standards for compounding quality nonsterile medications to help ensure patient benefit and safety. Which USP chapter provides these standards?

A) USP Chapter <795>
B) USP Chapter <797>
C) USP Chapter <800>
D) USP Chapter <825>
E) USP Chapter <839>



22) Celiac disease is a serious autoimmune disease. What is its main feature?

A) Malabsorption of proteins
B) Increased protein degradation
C) Decreased excretion of proteins
D) Decreased breakdown of proteins
E ) Increased saliva production



23) Immunoglobulins are a critical part of the immune response in our bodies. Which statement is not correct about them?

A) Immunoglobulins are also known as antibodies
B) The largest immunoglobulin is IgM
C) IgA is the first immunoglobulin to be synthesized in response to an antigen
D) only immunoglobulin that can pass through the placenta is IgG
E) none of the above



24) Approximately 415 million people have been diagnosed with diabetes this year. Which of the following terms is used for this situation?

A) Endemic
B) Epidemic
C) Incidence
D) Prevalence
E) Pandemic



25) The price of a product has increased by 10 percent, resulting in a large decline in its demand in the marketplace. Which of the following types of demand does this product follow?

A) Latent demand

B) Elastic demand

C) Inelastic demand

D) Unaffected demand

E) Immanent demand





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