Saudi Pharmacist Licensing Exam Questions
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101) A patient with ulcerative colitis is taking Mesalazine for the management of his condition. What supplement is recommended to be taken along with the said drug?
a) Vitamin B6
b) Folic acid
c) Iron
d) Vitamin B12
e) Calcium
102) The recommended daily dose of folic acid during lactation is;
a) 400 mcg
b) 500 mcg
c) 600 mcg
d) 800 mcg
e) 1200 mcg
103) The effects of four antihypertensive drug classes (A-D) on the renin-angiotensin system are shown in the following table;
| Parameters | Drug A | Drug B | Drug C | Drug D |
|---|---|---|---|---|
| Renin Conc. | 🠋 | 🠉 | 🠉 | 🠉 |
| Angiotensin-I Conc. | 🠋 | 🠉 | 🠉 | 🠉 |
| Angiotensin-II Conc. | 🠋 | 🠋 | 🠉 | 🠉 |
| Angiotensin Receptor | --- | --- | 🠋 | --- |
Which class is represented by drug -C?
A Diuretics
B Direct Renin inhibitors
C Angiotensin II receptor blockers
D Angiotensin-converting enzyme inhibitor
E) Adrenergics
104) The maximum daily dose of alprazolam for the management of anxiety in adults is;
a) 1.5 mg
b) 3 mg
c) 4 mg
d) 10 mg
e) 15 mg
105) Identify the area of the brain that is responsible for the higher cognitive functions like problem-solving, memory, judgment, language, behavior, etc.?
a- frontal lobe
b- temporal lobe
c- parietal lobe
d- occipital lobe
e- limbic lobe
106) Considering the structure-activity relationship of Aspirin, what will be the result of the substitution of halogen atoms on the aromatic ring?
a- all activity is lost
b- activity decreases
c- toxicity decreases
d- increases activity as well as toxicity
e- aspirin is transformed into ibuprofen
107) A patient is found to be allergic to penicillin therapy. Which medication among the following can be safely taken by this patient?
a- methicillin
b- doripenem
c- amoxicillin
d- azithromycin
e- cefixime
108) The correlation between INR and the risk of bleeding during warfarin therapy warrants that INR be maintained in a certain desirable range to achieve the optimum anticoagulant effect of warfarin. The recommended INR range is;
a- 2 to 3
b- 4 to 6
c- above 5
d- 6 to 8
e- 9 to 11
109) In antacids preparation, aluminum hydroxide and magnesium compounds are usually used in combination. The main reason behind this is;
a- to balance their constipative and purgative effects
b- to optimize activity in the stomach as well as the intestines
c- to reduce systemic absorption of each other
d- to prevent metabolic alkalosis
e- to correct electrolyte imbalance during PUD
110) Depilatory products are used for the purpose of;
a- nails care
b- hair treatment
c- hair removal
d- odor neutralization
e- skin tanning
111) The proton pump secretes hydrogen ions into the gastric lumen in exchange of;
a- Na+
b- K+
c- OH-
d- HCO3-
e- Cl-
112) Which of the following hormones is released in response to low blood glucose levels in the body?
a) Insulin
b) Glucagon
c) Adrenaline
d) Thyroxine
e) Renin
113) The most serious side effect of penicillin therapy can be?
a- Diarrhea
b- Renal damage
c- Fatty liver
d- Anaphylactic shock
e- 8th cranial nerve damage
114) Thiopental is a;
a- Ultra-short-acting barbiturate
b- Short-acting barbiturate
c- Intermediate-acting barbiturate
d- Long-acting barbiturate
e- benzodiazepine agent
115) The use of morphine is contraindicated in patients with head injury. This is because;
a- of its increased addiction potential
b- it causes cerebral vasoconstriction
c- it increases intracranial tension
d- it causes a massive release of histamine
e- all of the above
116) Drug(s) that can cause vitamin B12 deficiency;
a- Cholestyramine
b- Cimetidine
c- Colchicine
d- Phenobarbital
e- all of the above
117) Which drug among the following is not paired with its correct indication?
a- Colchicine – used to prevent or treat attacks of gout
b- Trimethoprim – used to treat urinary tract infections
c- Omeprazole – an antagonist for Valproic Acid overdose
d- Cholestyramine – used to lower high cholesterol levels in the blood
e- Famotidine – a histamine blocker used to treat and prevent ulcers
118) Which drug among the following can cause folate deficiency?
a- trimethoprim
b- pyrimethamine
c- triamterene
d- methotrexate
e- all of the above
119) The use of loop diuretics can cause which nutrient depletion?
a- calcium
b- magnesium
c- potassium
d- zinc
e- all of the above
120) The pharmacological class of Fusidic acid is;
a- antiviral
b- antibiotic
c- antifungal
d- antihyperlipidemic
e- antacid
121) Enteric coated tablet is meant to disintegrate in the;
a- mouth
b- stomach or intestine
c- stomach
d- intestine
e- anus
122) Type 2 diabetes drug that is known to cause vitamin B12 deficiency is;
a- metformin
b- glyburide
c- pioglitazone
d- acarbose
e- sitagliptin
123) An anti-asthmatic agent that is ineffective orally?
a- Theophylline
b- Metformin
c- Salbutamol
d- Montelukast Sodium
e- Sodium cromoglicate
124) Which of the following is NOT a function of the liver?
a) Detoxification of toxic substances
b) Production of bile
c) Regulation of blood glucose levels
d) Production of red blood cells
e) Digestion of food
125) One of the following antibiotics is NOT safe to use in the penicillin-allergic patient;
a- vancomycin
b- meropenem
c- doxycycline
d- ciprofloxacin
e- gentamicin
----------- Continued
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Answer Keys
MCQ # - Correct option
101-
102-
103-
104- c
105- a
106- d
107- d
108- a
109-
110- c
111- b
112- b
113- d
114- a
115- c
116- e
117- c
118- e
119- e
120- b
121- d
122- a
123- e
124- d
125- b
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